Journal article
A Brain Marker for Developmental Speech Disorders
AT Morgan, M Su, S Reilly, G Conti-Ramsden, A Connelly, FJ Liégeois
Journal of Pediatrics | Published : 2018
Abstract
Objective: To characterize the organization of speech- and language-related white matter tracts in children with developmental speech and/or language disorders. Study design: We collected magnetic resonance diffusion-weighted imaging data from 41 children, ages 9-11 years, with developmental speech and/or language disorders, and compared them with 45 typically developing controls with the same age range. We used probabilistic tractography of diffusion-weighted imaging to map language (3 segments of arcuate fasciculus, extreme capsule system) and speech motor (corticobulbar) tracts bilaterally. The corticospinal and callosal tracts were used as control regions. We compared the mean fractional..
View full abstractGrants
Awarded by Centre of Excellence for Electromaterials Science, Australian Research Council
Funding Acknowledgements
Supported by the National Health and Medical Research Council (NHMRC) Centre of Research Excellence (CRE) (1023493 [to S.R., A.M., and A.C.]); NHMRC CRE (1116976 [to A.M., A.C., and S.R.]); NHMRC Career Development Fellowship (607315 [to A.M.]) and NHMRC Practitioner Fellowship (1105008 [to A.M.]); and a Hearing CRC grant (to S.R., A.M.) A.M., S.R., and A.C. are grateful to the Operational Infrastructure Support Program of the State Government of Victoria for their support. The authors declare no conflicts of interest.